Although anabolic steroids are commonly regarded as safe drugs, their use also depends on a variety of negative cosmetic, physical and psychological symptoms. Many of these side effects occur during the prescribed use of anabolic steroids, even if they occur dramatically during overdosing.
Nearly every consumer of anabolic steroids whether with a high-performance intention or with the intention of achieving optical improvements will experience undesirable side effects during application. In addition, anabolic steroids are capable of acting on internal processes which cannot be detected by the user at first.
In the following, an overview will be given as to which circuits internal processes and reactions are affected by the use of anabolic steroids.
The use of anabolic or androgenic steroids in overdosed form and even in the prescribed dosage can result in a multitude of negative effects on the cardiovascular system.
This is reflected in several areas including among others, an unfavorable increase in cholesterol, a thickening of the heart chambers, increased blood pressure and a changed reaction capacity within the vascular system. In simple terms, these preparations are very safe. The risk of myocardial infarction of an otherwise healthy person during a single steroid application cycle is negligible, as is the risk of stroke. However, a longer period of use also increases the period during which undesired side effects can be multiplied and sometimes consumer may fall into serious liver conditions. A premature death due to myocardial infarction or stroke is a clear risk in the long-term intake of anabolic steroids. In order to better understand these risks, one has to be aware of the exact mode of action of steroids on the cardiovascular system.
The human immune system reacts primarily to sex hormones. This results in functional differences between the sexes. Women tend to have a more active immune system than men and are more resistant to bacterial and other infections.
For this, the female immune system is more susceptible to autoimmune diseases. To the higher action level, the Daily Immune status is again subject to the hormonal fluctuations of the menstrual cycle which also proves the strong influence of sex hormones. Thus the slightly weaker defense strength of men can apparently be attributed to the testosterone which here functions as an immunosuppressive hormone. Androgens can therefore directly alter the immune system – either by their conversion into estrogens or by the alteration of the glucocorticoid circulation.
Anabolic steroids have shown both immune stimulatory and immunosuppressive activities in animal experiments. Due to the fact that these preparations can influence the immune system through a variety of possibilities and that anabolic steroids are a multifaceted drug class, the effects on the immune system always depend on the respective conditions.
In the use, changes in the immune system are usually negligible and lead to no relevant immune stimulatory or immunosuppressive actions and that may result in a serious liver condition. Anabolic steroids have also been used in many patients with weakened immune systems, e.g. In the case of muscle wasting in conjunction with an HIV infection, without a relevant change in the immune system or the tumor markers being detectable.